A tailored probiotic addition to the enzyme supplement, for example, lactase in the treatment of lactose intolerance and pancreatic enzymes in the treatment of pancreatic insufficiency, seems to offer an advantage to the therapeutic management of such disorders.

Protease supplementation attenuates muscle strength losses after eccentric exercise by regulating leukocyte activity and inflammation.

Appropriate use of pancrelipase in patients with pancreatic exocrine insufficiency can achieve symptomatic relief, prevent morbidity/mortality, and improve quality of life.